Study of Prevalence and Risk Factors of Hypovitaminosis C in Long Term Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Vitamin C plasma level
研究概览
简要总结
The clinical finding of skin rashes which appear after a vitamin C deficiency in Long Term Care Unit leads us to believe that the institutional diet could predispose to this kind of deficiency. Vitamin C has a key role into the struggle against oxidant stress and is involved into the connective tissue formation of the skin and the vascular endothelium. Vitamin C deficiency affects currently 15 to 25% of the elderly over 65 years old reaching 15% women and 20% men after 65 according to Johnston and Al. It concerns mainly the people in precarious situations (persons without fixed homes, ethyl-smoking persons) and elderly over 65 years. Hypovitaminosis C, defined by plasma level between 5 mg/L and 15 mg/L (28.41 to 85.23 µmol/L), is currently undiagnosed, especially with people with a risk of food deficiency and its prevalence increases with age. The treatment consists of a daily oral supplementation of 1 gram of vitamin C/d for 15 days. A minimum intake of 10 mg/D of vitamin C is required to prevent scurvy and maintain a total pool of 350 mg. A diet modification by a systematic intake of 2 glasses of fresh orange juice and/or the consumption of raw fruits and vegetables would prevent the appearance of scurvy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female over 65 years old
- •living in the Unit of Long Term Care without any limit time.
- •with a system of social insurance
- •Who gave its consent by his own , or with help of his representant or his tutor or curator.
排除标准
- •rejection of the blood sample
- •patient feeding with articial nutritional feeding (stomach tube feeding)
- •person close to death, who is not able to feed himself and / or with life-threatening in short time.
- •Patient with personal history of vitamin C deficiency.
研究组 & 干预措施
Patient living in the Unit of Long Term Care
Patient living in the Unit of Long Term Care without any limit time
干预措施: Blood sample (Procedure)
结局指标
主要结局
Vitamin C plasma level
时间窗: Between day 0 and day 7.
1. ) Collection of the consent 2. ) At the same time as other analysis for current cares a blood sample taken by a nurse of our unit to determine plasma levels of vitamin C. 3. ) Registration of risk factors of vitamin C deficiency. . 4. ) Doing a clinical exam within 7 days after the blood sample.
次要结局
- Cutaneous symptoms(Day 0)
- Supposed risk factors of hypovitaminosis C(Day 0)
