Can pupil diameter changes predict individual variability of opioid sensitivity?
Not Applicable
- Conditions
- Patients undergoing laparoscopic hysterectomy
- Registration Number
- JPRN-UMIN000039582
- Lead Sponsor
- Teikyo University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
Patients receiving regional anesthesia, taking opioids, having contraindication for drugs planned to use. Patients with diabetes mellitus, psychotic and neurological diseases. Patients taking beta blocking agents, anti-cholinergic agents, and anti-psychotic drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association between the percent decrease in the pupil diameter following a small dose of fentanyl and remifentany consumption during surgery (normalized with ideal body weight and duration of anesthesia). Association between the percent decrease in pupil diameter following a small dose of fentanyl and postoperative fentanyl consumption within 24 h after surgery (normalized with body weight).
- Secondary Outcome Measures
Name Time Method