Simultaneous effect of three dexmedetomidine administration methods on hemodynamic responses following laryngoscopy

Phase 3

Conditions: Hemodynamic variables.
Other complications of anesthesia
T88.59

Registration Number: IRCT20141001019359N15

Lead Sponsor: Bojnourd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 120

Inclusion Criteria

The Patient must be between 20 and 60 years old
ASA physical status I-II
The Patient must not have any intranasal lesions
The patient must not have cardiovascular problems
The patient must not have asthma or respiratory illness

Exclusion Criteria

Patients who are addictive or have drug abuse
Patients with an unanticipated difficult airway.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in hemodynamic parameters during intubation. Timepoint: After induction of anesthesia, in the first 5 minutes after intubation, every 1 minute after induction and on minutes 7 and 10. Method of measurement: Using the monitoring device.

Secondary Outcome Measures

Name	Time	Method
Hemodynamic responses during skin incision. Timepoint: Skin incision time. Method of measurement: Patients' response to skin incision will be recorded as yes/no (no if less than 20% changes in hemodynamic parameters and yes if more than 20% changes are observed in them).;Patient's sedation status. Timepoint: At the entering of the operating room and then 40 minutes after the interventions. Method of measurement: Ramsey's sedation scale.;Extubation time after reversal of neuromuscular relaxant. Timepoint: From the time of administration of Neostigmine to removal of the endotracheal tube. Method of measurement: chronometer.;Post-operative nausea and vomiting. Timepoint: 2 hours after the operation. Method of measurement: In the form of presence or absence.;Sore throat after operation. Timepoint: 2 hours after the operation. Method of measurement: In the form of presence or absence.