Effectiveness of transdermal buprenorphine patch on pain relief after spinal surgery
Phase 4
Completed
- Conditions
- Health Condition 1: null- Postoperative patients of elective spinal instrumentation surgery
- Registration Number
- CTRI/2017/03/008018
- Lead Sponsor
- Bangur Institute of Neurology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
ASA I or ASA II
Age between 20-50 yrs
Weight between (50-65kg)
Patients of either sex.
Patients scheduled for elective spinal instrumentation surgery
Anticipated duration of surgery 2-3 hrs.
Exclusion Criteria
Patient refusal
Neurological disorders and history of seizure
Patient on CNS depressant drug
Known allergic to opioids
Opioid dependent patient
Hemodynamically compromised patients
Patient with hepatic impairment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to requirement of first rescue analgesic doseTimepoint: 48 hours postoperatively
- Secondary Outcome Measures
Name Time Method Degree and Duration of postoperative analgesia by VAS score. <br/ ><br>Timepoint: 48 hours postoperatively;Degree of postoperative sedation by RAMSAY Sedation score.Timepoint: 48 hours postoperatively;Frequency of requirement of rescue drug (inj tramadol 2mg/kg) during <br/ ><br>postoperative period.Timepoint: 48 hours postoperatively;Hemodynamic changes in intraopertive and postoperative periodTimepoint: 48 hours postoperatively;Total intra operative consumption of fentanyl.Timepoint: 48 hours postoperatively