The Study on the Spatial Distribution of Prostate Cancer by Modified Trans-perineal Template-guided Mapping Biopsy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- the spatial distribution based on the biopsy tissue
研究概览
简要总结
Investigators plan to use modified TTMB technology to puncture prostate of participants suspected prostate cancer, especially those with the first negative biopsy , but having a rising PSA.Then, Investigators will simulate the spatial distribution of prostate cancer in patients with positive biopsy before radical prostatectomy by way of the TPS software system . And after the radical prostatectomy ,Investigators will simulate the spatial distribution with the help of large tissue slice technique to compare with preoperative simulation ,which to verify the two simulations are consistent.
详细描述
Investigators mainly plan to determine the accuracy of the modified TTMB technology in combination with the TPS system on the location of the tumor space distribution by comparing the two simulation, which is significant for the accurate focal thearpy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •1.Male patients;
- •2.18 yrs and older, and 90 yrs and younger;
- •3.Rectal examination reveal prostate nodules;
- •4.B ultrasound, CT or MRI find abnormal images;
- •5.PSA>4ng/ml, abnormal f/t ratio and PSAD
排除标准
- •Abnormal coagulation function;
- •Severe urinary tract infection;
- •Serious cardiovascular and cerebrovascular disease
结局指标
主要结局
the spatial distribution based on the biopsy tissue
时间窗: 2 years
to simulate the spatial distribution of cancer based on the biopsy tissue contained cancer with the help of TPS system
次要结局
- the spatial distribution based on the large tissue slice technique(2 years)
研究者
Xuefei Ding,MD
Chief physician of urology
Subei People's Hospital of Jiangsu Province