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Clinical Trials/NCT01303770
NCT01303770
Unknown
Not Applicable

Development and Evaluation of a Cognitive Rehabilitation Program for Persons With Multiple Sclerosis

Tel Aviv University1 site in 1 country50 target enrollmentFebruary 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
Tel Aviv University
Enrollment
50
Locations
1
Primary Endpoint
Cognitive strategy use
Last Updated
12 years ago

Overview

Brief Summary

Multiple sclerosis (MS) is a progressive neurological disease that affects over 2.5 million people worldwide. Up to 50% of persons with MS (PwMS) will experience some form of cognitive impairment as a result of the disease including disturbances in memory, attention, concentration, information processing, and executive functions such as problem solving, and self-monitoring. MS-related cognitive impairments negatively affect many aspects of functioning and independent participation in everyday life. Thus, PwMS who experience cognitive impairments face a wide array of recurring barriers that pose grave challenges to carrying out everyday activities while trying to maintain multiple life roles and as they age.

Management of cognitive symptoms can be addressed through rehabilitation which has the potential to reduce disability, prevent complications of the disease, and enhance participation, independence, and quality of life. Considering the high frequency of cognitive impairments in MS and their significant, complex impact on functioning and independence, it is critical that cognitive interventions be an essential component of MS rehabilitation.

The overarching goal of this study is to develop and test a self-management, group-based cognitive rehabilitation program designed specifically for PwMS.

Registry
clinicaltrials.gov
Start Date
February 2011
End Date
December 2014
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Eynat Shevil

Dr. Eynat Shevil

Tel Aviv University

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of MS
  • 18 years of age or older
  • Self-report of cognitive difficulties

Exclusion Criteria

  • Exacerbation of symptoms in past 3 months
  • History of TBI, CVA, epilepsy, Psychiatric condition, drug/alcohol abuse

Outcomes

Primary Outcomes

Cognitive strategy use

Time Frame: pre intervention, post intervention, 3,6,12 month followup

Secondary Outcomes

  • Cognitive self-efficacy(pre-intervention, post intervention, 3,6,12 month followup)

Study Sites (1)

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