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临床试验/NCT01303770
NCT01303770Unknown不适用

Development and Evaluation of a Cognitive Rehabilitation Program for Persons With Multiple Sclerosis

Tel Aviv University2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2011年2月最近更新:
适应症

试验速览

阶段
不适用
入组人数
50
试验地点
2
主要终点
Cognitive strategy use

研究概览

简要总结

Multiple sclerosis (MS) is a progressive neurological disease that affects over 2.5 million people worldwide. Up to 50% of persons with MS (PwMS) will experience some form of cognitive impairment as a result of the disease including disturbances in memory, attention, concentration, information processing, and executive functions such as problem solving, and self-monitoring. MS-related cognitive impairments negatively affect many aspects of functioning and independent participation in everyday life. Thus, PwMS who experience cognitive impairments face a wide array of recurring barriers that pose grave challenges to carrying out everyday activities while trying to maintain multiple life roles and as they age.

Management of cognitive symptoms can be addressed through rehabilitation which has the potential to reduce disability, prevent complications of the disease, and enhance participation, independence, and quality of life. Considering the high frequency of cognitive impairments in MS and their significant, complex impact on functioning and independence, it is critical that cognitive interventions be an essential component of MS rehabilitation.

The overarching goal of this study is to develop and test a self-management, group-based cognitive rehabilitation program designed specifically for PwMS.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of MS
  • 18 years of age or older
  • Self-report of cognitive difficulties

排除标准

  • Exacerbation of symptoms in past 3 months
  • History of TBI, CVA, epilepsy, Psychiatric condition, drug/alcohol abuse

结局指标

主要结局

Cognitive strategy use

时间窗: pre intervention, post intervention, 3,6,12 month followup

次要结局

  • Cognitive self-efficacy(pre-intervention, post intervention, 3,6,12 month followup)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Eynat Shevil

Dr. Eynat Shevil

Tel Aviv University

研究点 (2)

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