The Development of Diagnosis and Prognosis Predictive Model for Peripheral Nerve Disease

Completed

• Conditions: Peripheral Nerve Disease

• Registration Number: NCT06843642
• Lead Sponsor: Wuhan Union Hospital, China

Brief Summary

This is a retrospective observational cohort study (MRN-PND), aiming to explore the utility of contrast-enhanced MRN (ceMRN) compared to plain MRN in diagnosing peripheral nerve diseases and predicting the prognosis of patients with these conditions. Additionally, artificial intelligence (AI) methods are employed to enhance the diagnostic accuracy of MRN for peripheral nerve diseases and to precisely predict disease outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01-01
• Primary Completion: 2025-01-01
• Study Completion: 2025-01-01
• Status Verified: 2025-02
• Study First Submitted: 2025-02-12
• Study First Submitted QC: 2025-02-24
• Last Update Submitted: 2025-02-24
• Study First Posted: 2025-02-25
• Last Update Posted: 2025-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

1. Patients who underwent MRN scanning at Wuhan Union Hospital between January 2015 and January 2025;
2. Age > 18 years;
3. Definitive clinical diagnosis (either healthy individuals or patients with a specific condition).

Exclusion criteria：

1. Poor quality of imaging;
2. Incomplete clinical data or loss to follow-up;
3. Unclear clinical diagnosis.

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation analysis of MR information and diagnosis outcome	0.5 year	The indicator is the area under the curve of the predict diagnosis outcome.

Trial Locations

Locations (1)

Union Hospital，Tongji Medical College，Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China