Solar Lighting Intervention Trial to Reduce Indoor Air Pollution and Improve Adult Respiratory Health in Rural Uganda
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Fine particulate matter (PM2.5) and Black Carbon
研究概览
简要总结
This study evaluates the impact of a solar lighting system on kerosene lamp use, levels of indoor air pollution, and health in women living in rural Uganda. Half of the participants will receive the lighting systems immediately, while the other half will receive them after an 18 month delay.
详细描述
One fifth of the global population relies on kerosene lamps for lighting, yet few studies have focused on kerosene lighting as a source of indoor air pollution. In our preliminary studies performed in Uganda, we show that homes using solar lighting have much lower levels of indoor air pollution compared to homes using kerosene lighting. The primary goal of this study is to determine the extent to which solar lighting will reduce kerosene use and indoor air pollution in rural Uganda, whether this intervention improves lung health, and to identify the role bacteria in our gut have on determining whether or not people will get sick from indoor air pollution.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Randomization will be performed using dummy codes to represent intervention and control groups by an independent statistician; blinding of the intervention to the participants and field team is not possible, but data analysis will take place prior to unblinding.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women living in Nyakabare Parish, Uganda with no prior history of chronic lung disease
排除标准
- •Current active tuberculosis in any family member
研究组 & 干预措施
Control (usual lighting)
Participants will continue to use their usual lighting sources.
Intervention (solar lighting)
Participants will receive an indoor solar lighting system
干预措施: Solar lighting system (Other)
结局指标
主要结局
Fine particulate matter (PM2.5) and Black Carbon
时间窗: 48 hour
Sampling for PM2.5 and Black Carbon over 48 hours will be collected
次要结局
- Daily use of solar lighting system (hours per day)(baseline, 3 months, 6 months, 12 months after the intervention)
- Blood pressure(baseline, 3 months, 6 months, 12 months after the intervention)
- Qualitative interviews(Post-intervention)
- Forced Expiratory Volume in one Second (FEV1)(baseline, 3 months, 6 months, 12 months after the intervention)
- Heart rate variability(baseline, 3 months, 6 months, 12 months after the intervention)
- Stool microbiome(baseline, 3 months, 6 months, 12 months after the intervention)
- Respiratory symptoms(baseline, 3 months, 6 months, 12 months after intervention)
研究者
Peggy S Lai
Assistant Professor
Massachusetts General Hospital