The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit

Not Applicable

Completed

• Conditions: Sepsis; Respiratory Failure; Renal Failure; Surgical Site Infection

• Registration Number: NCT00282594
• Lead Sponsor: Genesys

Brief Summary

We sought to determine if there is a benefit to using an insulin drip to control hyperglycemia in the surgical critical care unit for patients who undergo general and vascular surgery.

Detailed Description

While evidence exists for using tight glycemic control in the critically ill cardiac surgical patient, other patient populations have yet to be studied. We performed a prospective randomized trial for using intensive insulin therapy in the general and vascular critically ill surgical patient population. We will compare tight glycemic control versus conventional glycemic control to determine if there is a benefit to the normalization of blood glucose levels in this patient population

Study Timeline

• Study Start: 2003-07
• Study Completion: 2005-10
• Status Verified: 2005-11
• Study First Submitted: 2006-01-26
• Study First Submitted QC: 2006-01-26
• Last Update Submitted: 2006-01-26
• Study First Posted: 2006-01-27
• Last Update Posted: 2006-01-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 317

Inclusion Criteria

Patients undergoing a general or vascular surgical procedure requiring admission to the surgical intensive care unit as a result of ventilatory requirement, vasopressor support, or physiologic instability

Exclusion Criteria

• Under age 18

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Mortality

Secondary Outcome Measures

Name	Time	Method
Length of ICU Stay
Ventilatory Requirement
Vasopressor Support
Incidence of Renal Failure
Incidence of Wound Infection

Trial Locations

Locations (1)

Genesys Regional Medical Center; 🇺🇸 Grand Blanc, Michigan, United States