Development of a new transcranial magnetic stimulation therapy for treatment-resistant depression and identification of its predictor of response
Phase 2
Recruiting
- Conditions
- Treatment-resistant depression(TRD)
- Registration Number
- JPRN-UMIN000028855
- Lead Sponsor
- Department of Neuropsychiatry, Keio University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Persons with cerebral organic diseases (e.g., intracranial organic lesions of moderate severity or higher, neurodegenerative diseases, etc.) (2) History of convulsive seizures or epilepsy (3) Substance-related disorders in the past 6 months (4) Serious or unstable physical illness (5) Undergone rTMS treatment or ECT within the past 6 months (6) Any contraindication to TMS or MRI procedures such as metal implants, pacemakers, claustrophobia, etc. (7) Patients whose head, neck, or body size is not suitable for MRI scanner (8) Other cases that the principal investigator and subinvestigators deem inappropriate as research subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All participants will received the following measures at time . Montgomery Asberg Depression Rating Scale (MADRS), 16-item Quick Inventory of Depressive Symptoms-Japanese version (QIDS16-J) Maintenance phase: Montgomery Asberg Depression Rating Scale (MADRS), 16-item Quick Inventory of Depressive Symptoms-Japanese version (QIDS16-J)
- Secondary Outcome Measures
Name Time Method