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Timing of Treatment Completion in Staged Selective Laser Trabeculoplasty (SLT): Early vs. Late Completion

Phase 3
Terminated
Conditions
Glaucoma
Interventions
Procedure: selective laser trabeculoplasty - early completion
Procedure: Selective laser trabeculoplasty - late completion
Registration Number
NCT00551395
Lead Sponsor
Queen's University
Brief Summary

This study will evaluate the effect of the timing of treatment completion in two-staged selective laser trabeculoplasty therapy on intraocular pressure lowering effect.

Detailed Description

SLT therapy is used as an IOP lowering agent in patients with glaucoma. It is unknown whether the timing of a 2-staged approach to the laser therapy will result in better IOP lowering effect.

This study will evaluate the timing (early vs. late completion of SLT therapy) and determined the IOP lowering effect following the interventions.

Arm 1: Early Completion SLT

180 degrees of SLT on Day 1, 180 degrees of SLT on the other 180 degrees on Day 2

Arm 2: Late Completion SLT

180 degrees of SLT on Day 1, 180 degrees of SLT on the other 180 degrees at the 1 month follow up visit.

Primary Outcome: IOP (mmHg).

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • 18 years of age
  • primary open angle glaucoma or pseudoexfoliation glaucoma
Exclusion Criteria
  • Unable to give informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
SLT Early Completion (Arm 1)selective laser trabeculoplasty - early completionIntervention: 180 degrees of laser on Day 1, 180 degrees of laser on the other 180 degree on Day 2
SLT Late Completion (Arm 2)Selective laser trabeculoplasty - late completionIntervention: 180 degrees of laser on Day 1, 180 degrees of laser on the other 180 degrees at 1 month follow up appointment.
Primary Outcome Measures
NameTimeMethod
intraocular pressure lowering1 month following procedure
Secondary Outcome Measures
NameTimeMethod
intraocular pressure lowering3, 6, 12 and 24 months following procedure

Trial Locations

Locations (1)

Hotel Dieu Hospital & Queen's University

🇨🇦

Kingston, Ontario, Canada

Hotel Dieu Hospital & Queen's University
🇨🇦Kingston, Ontario, Canada
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