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临床试验/CTRI/2025/11/097559
CTRI/2025/11/097559尚未招募4 期

A Randomised comparative clinical trial to evaluate the efficacy of scaling followed by pratisarana with dasanasamskara churna ,laxadi churna and yastimadhu ghrita kavala in the management of upakusha (periodontitis).

Dr Guruswamy M K2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年12月20日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
100
试验地点
2
主要终点
reduction in bad odour from mouth and bleeding gums ,tartar over tooth and scaling over the teeth

研究概览

简要总结

Upakusha is one among the dantamoolagata roga, caused by pitta and rakta dushti characterized by paaka, raktasraava, shotha, daaha, manda vedana, poothi mukha. The samanya chikitsa includes Vamana, Virechana, Shirovirechan, Raktamokshana, Pratisarana, Kavala and Raktapitta chikitsa. If left untreated, it may leads to Saushira, Mahasaushira . Upakusha can be correlated with Periodontitis.

Periodontitis is an inflammatory disease of supporting tissues of the tooth, caused by single or multiple microorganisms resulting in progressive destruction of the periodontal ligament and alveolar bone with pocket formation. It is characterized by redness, swollen gums, bleeding gums, burning sensation; foul smell from mouth. The prevalence of chronic periodontitis in the urban population was found to be 42.3% (localized form - 29.3% and generalized form - 13%).

The management includes cleaning the pockets around the tooth, the teeth involved by periodontal disease can be saved if the bone loss has not been too extreme, irritants are removed by scaling and curettage and pocket are eliminated by gingival recession or by surgical removal of gingiva; osseous deformities are eliminated and tooth supporting tissues are recontoured to a normal physiologic architecture; occlusal force are balanced; and systemic factors are corrected. Finally gingivectomy and gingivoplasty, which are quite expensive and cause lot of inconvenience to the patients.

To develop a cost effective and safe Ayurveda treatment protocol for management of Upakusha (periodontitis) this clinical study of lekhana (scaling), dasanasamskara choorna  pratiasarana and yashtimadhu ghrita kavala is being taken up.

Lekhana (scaling), laakshadi choorna  pratiasarana and yashtimadhu ghrita kavala is taken as control.

Lekhana (scaling) does rakta shodhana by causing raktamokshana. Pratisarana of laakshaadi churna and dashana samskaara churna helps in alleviating the symptoms as their ingredients have shodhana, lekhana and ropana properties.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
12.00 Year(s) 至 40.00 Year(s)(—)
性别
All

入选标准

  • 1.Aged between 12-40 yrs of either sex.
  • 2.Patients diagnosed as upakusha (Mild to moderate chronic periodontitis).

排除标准

  • 1.Patients having dental caries, sinuses of gums and oral cancers.
  • 2.Patient on blood thinning medications.
  • 3.Pregnant woman 4.Haemorrhagic disorders.
  • 5.Necrotizing periodontitis 6.Patients contraindicated for scaling.

结局指标

主要结局

reduction in bad odour from mouth and bleeding gums ,tartar over tooth and scaling over the teeth

时间窗: 7days

次要结局

  • complete abscence of bad odour from mouth and bleeding gums and scaling over the teeth(45days)

研究者

发起方
Dr Guruswamy M K
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Guruswamy M K

J S Ayurveda mahavidyalaya and P D Patel Ayurveda Hospital Nadiad,Gujarat.

研究点 (2)

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