Erector Spinae Plane Block in Liver Transplantation Donors

Not Applicable

Completed

• Conditions: Pain, Postoperative
• Interventions: Procedure: Erector Spinae Plane Block; Procedure: Intravenous fentanyl patient control device

• Registration Number: NCT05406388
• Lead Sponsor: Medipol University

Brief Summary

Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision. Therefore adequate analgesia is important for recovery.

Erector Spinae Plane Block (ESPB) is a safe anesthesia technique used to provide postoperative analgesia. This study aimed to compare the novel ultrasound-guided ESPB technique with controls in terms of postoperative opioid consumption and postoperative pain control on donor patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-24
• Study First Submitted: 2022-06-01
• Study First Submitted QC: 2022-06-01
• Study First Posted: 2022-06-06
• Primary Completion: 2023-05-01
• Status Verified: 2023-08
• Study Completion: 2023-08-01
• Last Update Submitted: 2023-08-03
• Last Update Posted: 2023-08-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 41

Inclusion Criteria

• Donor patients scheduled for elective hepatectomy in liver transplantation surgery
• ASA I-II
• Patients who are aged between 18-65

Exclusion Criteria

• Patients who do not accept the procedure
• Skin infection at the site of Erector Spina Plan Block area
• Coagulation disorder or using anticoagulant drugs
• Known local anesthetics and opioid allergy
• Severe pulmonary and/or cardiovascular problems
• Substance addiction or known psychiatric or mental problems
• Chronic painkiller usage
• Pregnancy or lactation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Erector Spinae Plane Block	Erector Spinae Plane Block	Erector Spinae Plane Block for Postoperative Analgesia
Control group	Intravenous fentanyl patient control device	No regional anesthesia technique will be applied to the control group.

Primary Outcome Measures

Name	Time	Method
Opioid consumption	Change from baseline opioid consumption at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours	The amount of fentanyl required by the patient and given by the device will be recorded for the first 48 hours.

Secondary Outcome Measures

Name	Time	Method
Visual Analog Scale	Change from baseline pain scores at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours	Pain of patients will be evaluated and recorded according to the Visual Analog Scale.

Trial Locations

Locations (1)

Istanbul Medipol University Hospital; 🇹🇷 Istanbul, Turkey