Clinical Validation of an iPhone ECG System, QT Substudy
Overview
- Phase
- Not Applicable
- Intervention
- iPhone ECG
- Conditions
- Cardiac Arrhythmia
- Sponsor
- University of Oklahoma
- Enrollment
- 29
- Locations
- 1
- Primary Endpoint
- QT interval measurement (in milliseconds)
- Status
- Completed
- Last Updated
- 25 days ago
Overview
Brief Summary
This study will validate the recording accuracy of a specific electrical interval of the heart, the QT interval, between an iPhone rhythm strip recording and a traditional 12-lead electrocardiogram (ECG). These measurements will occur in hospitalized patients that are starting either sotalol or dofetilide, since both of these medications can prolong the QT interval.
Detailed Description
Patients that were already selected to begin either dofetilide or sotalol in the hospital, will be included in the study. Patients will receive an ECG before and 2 hours after each dose of the medication, which is done to monitor the QT interval. In addition, patients that consent to participate in the study will have an iPhone ECG recording taken in lead positions that correspond to leads I,II, and III. These recordings will be compared and analyzed to assess the accuracy of the QT interval recordings between the two methods.
Investigators
Eligibility Criteria
Inclusion Criteria
- •initiation of sotalol or dofetilide
- •inpatient at University hospital
Exclusion Criteria
- Not provided
Arms & Interventions
iPhone ECG QT recording
iPhone ECG
Intervention: iPhone ECG
Outcomes
Primary Outcomes
QT interval measurement (in milliseconds)
Time Frame: Participants will be followed for duration of hospital stay during which dofetilide or sotalol are being started, an expected average of 3 days
The QT interval (measured from the start of the QRS to the end of the T wave) will be measured on the 12-lead ECG and on the iPhone rhythm strip recording. Both measurements will be recorded in milliseconds and will be statistically analyzed for bias and agreement.