Volatile Anesthetic Protection Of Renal transplants 2

Recruiting

• Conditions: 10029149; niertransplantatie; kidney transplantation

• Registration Number: NL-OMON50373
• Lead Sponsor: anesthesiologie- onderzoeksbureau

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

-Age > 18 years
-Written informed consent
-Patients scheduled for kidney transplantation with a kidney from a DBD or DCD
donor

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
high immunological risk as determined bij local practice
Patients of the ABO-incompatible program

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>DGF defined as need of dialysis the first week after transplantation, excluding<br /><br>one time dialyses for hyperkalemia within 24 hrs after reperfusion. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Graft and patient survival<br /><br>GFR at 3, 12 months measured by 24h creatinin clearance<br /><br>the incidence of biopsy proven and treated acute rejection the first year after<br /><br>transplantation<br /><br>PNF defined as a permanent lack of function of the allograft<br /><br>Length of hospital stay<br /><br>Postoperative complications of all kind<br /><br>kidney biomarkers </p><br>