Study on the intervention of people with dampness syndrome hyperuricemia

Not Applicable

Recruiting

• Conditions: Hyperuricaemia

• Registration Number: ITMCTR2024000058
• Lead Sponsor: Guangdong Hospital of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

People aged between 18 and 75 years (including 18 and 75 years)
Diagnosis of hyperuricemia
Diagnosis of dampness syndrome
Informed consent is signed by participants.

Exclusion Criteria

1.People with secondary hyperuricemia, such as hyperuricemia secondary to malignant tumors, blood diseases, kidney diseases, chronic poisoning, etc;
2.People who have a history of alcoholism and have not abstained in the last 3 months
3.one or more previous episodes of gouty arthritis;
4.In the past 4 weeks, the subjects have taken uric acid lowering drugs, or drugs that can cause increased blood uric acid(1) Antituberculosis drugs: pyrazinamide/ethambutol/isoniazid, (2) low-dose aspirin, (4) loop diuretics and thiazide diuretics and antihypertensive drugs containing diuretics, (5) niacin, (6) high-dose vitamin C, (7) tumor chemotherapeutics, (8) cyclosporine;
5.Pregnancy and lactation, or the possibility of pregnancy and failed to take effective contraceptive measures;
6.Glutamic pyruvic transaminase or glutamic oxalacetic transaminase or creatinine is 2 times or more than the normal value;
7.Subjects with severe organic diseases, mental disorders or other reasons can not cooperate with treatment;
8.Allergic or ineffective to the test drug ingredient.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Score of dampness syndrome;Blood uric acid drop number;

Secondary Outcome Measures

Name	Time	Method
Incidence of hyperlipidemia;Cardiovascular event incidence;Joint ultrasound;hsCRP;TNF-a;Incidence of hyperlipidemia;IL-6;Incidence of gout;Urinary beta-2 microglobulin;glomerular filtration rate;Blood and urine metabolites;Incidence of diabetes;coating on the tongue;Fecal flora;