Prediction of Fetal Lung Maturity

Not Applicable

Completed

• Conditions: Fetal Distress
• Interventions: Radiation: fetal lung volume; Radiation: pulmonary artery resistance index

• Registration Number: NCT03159234
• Lead Sponsor: Assiut University

Brief Summary

Diabetes is the most common medical complication of pregnancy in the united states four to five percent of pregnancies are complicated by diabetes.

Pregestational diabetes (diabetes diagnosed before pregnancy, type 1 or type 2 diabetes mellitus) comprises approximately 13 percent of all diabetes in pregnancy, while gestational diabetes ( diabetes with onset or first recognition in pregnancy) comprises the remaining 87 percent . The prevalence of pregestational diabetes has been increasing due to the increasing prevalence of type 2 diabetes in women of reproductive age . The mainstay of the medical management of pregestational diabetes involves frequent monitoring of blood glucose levels with adjustment of diet and insulin therapy to achieve normoglycemia. Normoglycemia is important because maintenance of maternal blood glucose concentration at or near normoglycemic levels decreases the likelihood of adverse pregnancy outcomes, such as miscarriage , congenital anomalies , macrosomia and fetal death.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04
• Primary Completion: 2017-04
• Status Verified: 2017-05
• Study Completion: 2017-05
• Study First Submitted: 2017-05-16
• Study First Submitted QC: 2017-05-17
• Last Update Submitted: 2017-05-17
• Study First Posted: 2017-05-18
• Last Update Posted: 2017-05-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 54

Inclusion Criteria

• All pregnant diabetic women
• 37 weeks gestational age .

Exclusion Criteria

• Women before 37 and after 39 weeks gestational age
• Pregnancies with known fetal anomalies that may potentially affect the lung maturity .
• Multiple pregnancies.
• Women received steroids for lung maturation after ultrasound image acquisition and before delivery .
• Women with premature rupture of membranes (prom)
• Pregnancies complicated by medical disorders other than diabetes mellitus .
• Failure to obtain an informed consent .

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Diabetic pregnant women	pulmonary artery resistance index	-
Diabetic pregnant women	fetal lung volume	-

Primary Outcome Measures

Name	Time	Method
APGAR score	5 minutes

Trial Locations

Locations (1)

Women Health Hospital - Assiut university; 🇪🇬 Assiut, Egypt