Evaluation of New Methods for Prediction of Fetal Lung Maturity in Diabetic Mothers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- APGAR score
研究概览
简要总结
Diabetes is the most common medical complication of pregnancy in the united states four to five percent of pregnancies are complicated by diabetes.
Pregestational diabetes (diabetes diagnosed before pregnancy, type 1 or type 2 diabetes mellitus) comprises approximately 13 percent of all diabetes in pregnancy, while gestational diabetes ( diabetes with onset or first recognition in pregnancy) comprises the remaining 87 percent . The prevalence of pregestational diabetes has been increasing due to the increasing prevalence of type 2 diabetes in women of reproductive age . The mainstay of the medical management of pregestational diabetes involves frequent monitoring of blood glucose levels with adjustment of diet and insulin therapy to achieve normoglycemia. Normoglycemia is important because maintenance of maternal blood glucose concentration at or near normoglycemic levels decreases the likelihood of adverse pregnancy outcomes, such as miscarriage , congenital anomalies , macrosomia and fetal death.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All pregnant diabetic women
- •37 weeks gestational age .
排除标准
- •Women before 37 and after 39 weeks gestational age
- •Pregnancies with known fetal anomalies that may potentially affect the lung maturity .
- •Multiple pregnancies.
- •Women received steroids for lung maturation after ultrasound image acquisition and before delivery .
- •Women with premature rupture of membranes (prom)
- •Pregnancies complicated by medical disorders other than diabetes mellitus .
- •Failure to obtain an informed consent .
结局指标
主要结局
APGAR score
时间窗: 5 minutes
次要结局
未报告次要终点
研究者
Mohammed Khairy Ali
Lecturer of obstetrics and gynecology
Assiut University
