Transcranial Direct Current Stmulation in Children with Unilateral Motor Deficits: A New Approach for Pediatric Rehabilitation.

Phase 3

Conditions: Cebrale Parese
Cerebral Palsy. Movement disorder after stroke
10007963

Registration Number: NL-OMON40332

Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 16

Inclusion Criteria

• Aged between 7-9 years.
• CP diagnosis.
• A score of 2 or 3 on the MACS (Manual Ability Classification System).
• Mild unilateral motor deficit.
• Ability to cooperate and follow directions.

Exclusion Criteria

• Epilepsy.
• Non removable metal plates in or near the head.
• Orthopaedic surgery in the past 3 months on upper limb.
• Gross motor deficits
• History of neurological or psychiatric disorders

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main objective of the study is to investigate the effect of a single tDCS<br /><br>session on motor learning in a young population. Motor learning is investigated<br /><br>in three independent motor tasks: 1) the JTT a well validated training and test<br /><br>for functional motor assessment that reflects activities of daily living 2) the<br /><br>finger-sequencing task and 3) a simple reaction time task which measure motor<br /><br>improvement in a quantitative manner. Motor learning is calculated as accuracy<br /><br>and reaction time in every stimulation condition in blocks of three (sessions)<br /><br>for all the independent motor tasks.<br /><br>Motor learning will be used to compare different stimulation conditions<br /><br>(prefrontal, cerebellar and sham).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To determine the main effect of each of the tDCS electrode configurations in<br /><br>children with mild CP on different motor tasks with regard to motor performance.<br /><br><br /><br>To determine if interactions are present between tDCS electrode configurations<br /><br>and specific motor tasks with regard to motor performance.<br /><br><br /><br>To determine the size of the interaction effects with regard to motor<br /><br>performance.<br /><br><br /><br>To determine the wash-out effect (the decline of the effect of the tDCS<br /><br>stimulation between conditions) of a single session tDCS effects on motor<br /><br>performance in children with mild CP. </p><br>