A Prospective Data Collection Study for the Evaluation of Performance and Safety of the Spectrum Dynamics Multi-purpose CZT SPECT Camera
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Dementia
- 发起方
- Spectrum Dynamics
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- CZT SPECT Image Acquisition
- 状态
- 已完成
- 最后更新
- 6年前
概览
简要总结
This study evaluates SPECT image data acquired from Spectrum Dynamics' multi-purpose CZT SPECT-CT camera. All subjects will undergo routine clinical Anger SPECT imaging and an additional SPECT acquisition on the CZT SPECT camera. Additionally some subjects will undergo CT on the CZT SPECT-CT camera. The quality of images from each device will be compared.
详细描述
The Spectrum Dynamics Multi-purpose CZT SPECT camera is a whole body SPECT (single photon emission computed tomography) scanner which utilises solid-state cadmium zinc telluride (CZT) detectors to visualise injected, or otherwise introduced, radioactivity in the human body. The CZT SPECT camera detects the location and distribution of gamma-emitting radionuclides in the body and produces 3 dimensional cross-sectional images through computed reconstruction of the data for the purpose of determining various metabolic and physiologic functions in the human body. In comparison to conventional sodium iodide (NaI) gamma camera (or Anger camera) technology, solid state CZT technology offers improved energy, spatial and temporal resolution, and higher count rates. Improvements in energy resolution and sensitivity thus enable the potential capability for enhanced quantification, simultaneous dual isotope imaging and dynamic imaging acquisition. The camera system also incorporates a multi-slice CT gantry and acquired SPECT and CT images can be combined to improve image reconstruction by allowing fusion of CT and SPECT image data for anatomic localisation referencing and CT attenuation correction of the SPECT image data.
研究者
入排标准
入选标准
- •Patient is clinically referred for scintigraphy using a radiopharmaceutical in the energy range of 40 - 220 keV emission
- •Patient is aged ≥18 years
- •Patient condition is stable
- •Patient is willing and able to undergo image acquisition on the MPC CZT SPECT camera with integrated CT in addition to standard clinical scintigraphy procedure
- •Patient must be willing and able to provide written informed consent
- •Patient must be affiliated to a social security scheme
排除标准
- •Patient with unstable medical condition
- •Patient is pregnant, nursing, or of childbearing potential and is not using adequate contraceptive methods
- •Patient is contra-indicated to undergo the scintigraphy imaging procedure for which they have been clinically referred
结局指标
主要结局
CZT SPECT Image Acquisition
时间窗: 1 day
Technical adequacy of acquired CZT SPECT images for demonstrating the location and distribution of gamma ray radionuclides within the body
CZT SPECT-CT Image Acquisition
时间窗: 1 day
Technical adequacy of acquired CZT SPECT-CT images for demonstrating the location and distribution of gamma ray radionuclides within the body
次要结局
- Comparative Quality of CZT and Anger SPECT Images(1 day)
- CZT SPECT Image Quality(1 day)
- Safety of the CZT SPECT Camera(Through study completion; anticipated to be 24 months)
- CZT SPECT-CT Image Quality(1 day)
- Comparative Quality of CZT SPECT-CT and Anger SPECT Images(1 day)
- Safety of the CZT SPECT Camera During Imaging Procedures(1 day)
- Safety of the CZT SPECT-CT Camera(Through study completion; anticipated to be 24 months)
- Safety of the CZT SPECT-CT Camera During Imaging Procedures(1 day)