In patients newly diagnosed with breast cancer, will those who receive educational materials about treatment-focused genetic testing experience outcomes (including anxiety, depression, decisional conflict, knowledge of treatment-focused genetic testing, uptake of genetic testing and/or surgery choice) that are no worse than in patients who undergo standard familial cancer centre consultation only.

Prince of Wales Hospital0 个研究点目标入组 120 人开始时间: 2010年6月17日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•Women aged between 18 and <50 years with early or locally advanced breast cancer will be eligible if they exhibit at least one of the following risk features:
•1. A strong family history of breast and/or ovarian cancer, that is There are now (with the new diagnosis) three or more close relatives on one side of the family with breast or ovarian cancer OR There are now (with the new diagnosis) at least two close relatives on one side of the family with breast or ovarian cancer PLUS a high-risk feature (breast cancer diagnosed before the
•age of 40, bilateral breast cancer, breast and ovarian cancer in the same woman, Ashkenazi Jewish ancestry, breast cancer in a male relative)
•2. No or minimal family history of breast and/or ovarian cancer AND presence of Bilateral breast cancer AND/OR Ashkenazi Jewish ancestry AND/OR Triple negative breast cancer (oestrogen and progesterone receptor and Human Epidermal growth factor Receptor 2 (HER2) negative tumour)

•Women who have already had genetic counselling at a Familial Cancer Clinic (FCC) and/or testing will
•be excluded. Women with metastatic breast cancer (Stage IV) will also be excluded, as their surgical options will be determined largely by disease characteristics rather than choice.

发起方