A Clinical Study To Evaluate The Efficacy Of internally Trimurti Agada And externally Vishghna Lepa In The Management Of Dushivishajanya Dadru With Special Reference To Recurrent Tinea A Single Arm Open Labelled Clinical Trial
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- The patient will be withdrawn from the study if patient complains of any adverse
研究概览
简要总结
Symptomatic relief drugs are available having action as anti-histaminic, antifungal,
topical application and systemic steroids having known side effects. Hence people
suffering from Tinea infections are turning towards safe and effective remedies in
Ayurveda. In Ayurveda, there are two types of Chikitsa i.e., Antahparimarjana
(internal administration) and Bahirparimarjana (external administration). In Twaka
vikara internal administration of Churna is recommended along with external
application of Lepa as well[3] One such formulation as Trimurthi Agada is first of all
mentioned by Acharya Charaka in visha chikitsa adhyaya, indicated in Twaka
vikara in the context of Sarva visha avastha. The same reference is also mentioned
in Sushruta Samhita [4]and Ashtanga Sangraha, but with different ingredients.
For the present research work, reference of Charaka Samhita will be taken.
Trimurthi Agada is a formulation indicated in Sarvavishahar yoga and it’s action is
less explored. It is mentioned in Prayoga Samuchhaya[5]
, panchama parichheda ,
Sarvavisha chikitsa adhyaya and Vishavaidyasarasamucchayam[6], uttarbhaga,
sarvavishahara chapter,40thsloka.Trimurthi Agada is one of the formulations
mentioned in both text books as sarvavishahara yoga. The yoga is purely herbal
combination of only three drugs namely Nimba, Nili and Karanja. Bhavana is done
with its own patra swarasa. [5] Vishghna Lepa which is mentioned by Acharya
Charaka in Sutrasthana 3rd Adhyay useful in different skin diseases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 19.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •This trial will include all the patients of Dadru having classical signs and symptoms like, Kandu (Itching), Raga (Erythema), Pidaka (Papillae), Mandalamudgatama (Discoid lesion with elevated border) along with sign and symptoms of Dushivisha like., Dhatukshaya, Vaivarnya, Avipaka, Arochaka irrespective of gender, religion, profession, socioeconomic stat Dadru which are Recurrent in nature (minimum 2 times in a year).
- •Patient willing to accept the participation in the clinical trial.
排除标准
- •Patient suffering from severe, or complicated systemic disease like, Chronic kidney disease, Liver disease and VDRL disease will be excluded from the trial study.
- •Dadru which are newly originated (Recurrent rate Less than 2 times in year).
- •Patients who are not willing for inclusion in the study.
- •Pregnant women.
结局指标
主要结局
The patient will be withdrawn from the study if patient complains of any adverse
时间窗: 60 days
reaction, not responding to the treatment or any serious complication occur due
时间窗: 60 days
to treatment will be referred to the higher center.
时间窗: 60 days
Between the trial period; if any serious complication develops requiring urgent
时间窗: 60 days
treatment such as pyoderma, prolonged fever due to infected skin lesions, patients
时间窗: 60 days
will be referred appropriately.
时间窗: 60 days
次要结局
- To study the efficacy of Trimurti agada and vishgna lepa in recurrent tinea in(every 15 days Till 60days)
研究者
Dr Ganesh venktarajam Mamidala
Sumatibhai Shah Ayurved mahavidyalaya hadpsar Pune