se of stem cells for treatment of chronic kidney disease
Phase 1
- Conditions
- Chronic Kidney Disease.Hypertensive renal disease
- Registration Number
- IRCT201509031031N17
- Lead Sponsor
- Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute for Stem Cell
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Inclusion Criteria: CKD confirmed with serum and urine analysis and GFR 25-60 mL/min; Male and Female; CKD (more than 3 months with increased and irreversible creatinine) symptoms; Patients with controlled hypertension; Patient's age between 40-60 years; Ability to understand and willingness to sign consent form
Exclusion Criteria
Pregnant or lactating; Vascular disease; Diabetes mellitus; Other systemic disease such as malignancy, autoimmune disease, hematologic disease, liver disease and …; Chronic rejection in transplantation; Life expectancy less than 2 years; Allergy to any ingredients used in cell culture; Congenital or acquired obstructive chronic renal failure; Unable to attend at follow up visits
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mass formation. Timepoint: Every three months. Method of measurement: Sonography.;Creatinine. Timepoint: 1,3,6,9,12 months after cell transplantation. Method of measurement: Blood Test.
- Secondary Outcome Measures
Name Time Method EGFR. Timepoint: 1,3,6,9,12 months after cell transplantation. Method of measurement: Scan isotope and GFR formula.