Etude Descriptive Retrospective de la Transfusion Plaquettaire Chez Des Patients Atteints d'hémopathie Maligne en Phase Palliative et Suivis au CHU de Besançon
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 119
- 试验地点
- 1
- 主要终点
- evaluate frequency of platelet transfusion at the end of life
研究概览
简要总结
Development of palliative care is less effective for patients with hematologic malignancies. Limited data is available for end of life care in this population, moreover with thrombocytopenic patients. Thrombopenia is a frequent complication, specific of bone marrow involvement in those diseases or its treatments. Yet, a few studies was interested in, whereas platelet transfusion is the only treatment indicated. As it represent a scarce, limited resource, the ethical principles are in conflict in this setting.
The purpose of this study was to describe retrospectively platelet transfusion in the six last few month of life of patients with hematologic malignancies at the CHU of Besançon (France) between 01/07/15 and 31/12/16.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with hematological malignancies
- •transfused in platelet at least once in the last 6 months of life
- •hospitalised or follow up at the CHU of Besancon at least once
- •dead during the period of the study
排除标准
- •patient with other oncologic malignancies
- •not transfused in platelet in the last 6 months of life
- •never hospitalised or follow up at the CHU of Besancon
结局指标
主要结局
evaluate frequency of platelet transfusion at the end of life
时间窗: 18 months (between 07/01/2015 and 12/31/2016)
to calculate the number of platelet transfusion at the end of life. The number of platelet transfusion between 6 months and death are collected in each periods of 2 weeks to calculate the number of transfusion per patient during each 2 weeks.
evaluate efficacy of prophylactic platelet transfusion at the end of life
时间窗: 18 months (between 07/01/2015 and 12/31/2016)
to calculate the platelet yield in percentage
evaluate efficacy of non prophylactic platelet transfusion at the end of life
时间窗: 18 month (between 07/01/2015 and 12/31/2016)
to calculate the transfusional interval between 2 platelet transfusion in days
次要结局
- demographic characteristic(18 months (between 07/01/2015 and 12/31/2016))