Evaluation of the effect of deep brain stimulation on the dopamine household in Parkinson*s disease.

• Conditions: Parkinson's disease; 10028037

• Registration Number: NL-OMON32074
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Patients with end-stage Parkinson*s disease, being scheduled for deep brain stimulation.

Exclusion Criteria

None.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The levodopa-induced change in synaptic dopamine concentration after versus<br /><br>before DBS.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The baseline dopamine receptor binding before and after DBS.</p><br>