MedPath

Evaluating The Acceptability and Uptake of Pre-Exposure Prophylaxis (PrEP) for Adolescent Women in The Deep South

Not Applicable
Withdrawn
Conditions
Adolescent Behavior
HIV/AIDS
PrEP
Registration Number
NCT03897725
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

This project is designed to 1) develop a PrEP implementation plan for a general adolescent clinic. Investigators will develop a replicable implementation plan for providing PrEP to adolescents in a primary care setting; and 2) Determine the acceptability and preliminary effectiveness of a telehealth intervention to promote adherence in adolescents.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria
  • Females between 15 to 21 years old
  • Established patients at the Adolescent Health Center
  • HIV negative
Exclusion Criteria
  • HIV positive patients
  • patients weighing less than 35kg
  • patients with creatinine clearance <60 ml/min
  • patients with documented osteopenia or osteoporosis or history of pathologic fractures
  • patients with previous allergic reactions to either emtricitabine or tenofovir
  • patients who are on post-exposure prophylaxis for HIV (they can become eligible after completion of therapy)
  • patients with hepatic impairment
  • For patients who become pregnant, they may be able to continue on PrEP after a discussion with their obstetrics/gynecology (OB/GYN) provider.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Adherence to PrEP1 year

Retention of adolescent females in PrEP care (attendance at follow-up visits) and adherence to emtricitabine/tenofovir evidenced by dried blood spot sampling

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

William A. Daniel Adolescent Health Center

🇺🇸

Birmingham, Alabama, United States

William A. Daniel Adolescent Health Center
🇺🇸Birmingham, Alabama, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.