Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19

Not Applicable

Completed

• Conditions: Covid19; Sars-CoV2
• Interventions: Procedure: Ophthalmologic exam

• Registration Number: NCT04385810
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

The management of patients with SARS-CoV2 in respiratory distress can expose to corneal or retinal lesions induced by the stay in intensive care.

Examination by ophthalmologists would make it possible to detect the most of the ophthalmologic problems known in intensive care and to provide an early, preventive or curative therapeutic response when possible, in order to avoid irreversible visual loss.

The object of the research is to assess the presence and the importance of surface ophthalmologic lesions, the presence and the importance of retinal or optic nerve lesions, in order to improve the monitoring and primary prevention of this population

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-27
• Study First Submitted: 2020-04-29
• Study First Submitted QC: 2020-05-12
• Study First Posted: 2020-05-13
• Primary Completion: 2020-07-29
• Study Completion: 2020-07-29
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-13
• Last Update Posted: 2020-11-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• patient SARS-CoV2 positive (RT-PCR or chest scanner)
• hospitalized in intensive care

Exclusion Criteria

• traumatic lesion of the face or any other condition preventing any ophthalmological evaluation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Ophthalmologic exam	Ophthalmologic exam	-

Primary Outcome Measures

Name	Time	Method
Describe tear film anomalies at day 0	Day 0	Shirmer test
Describe ophthalmologic damage to the cornea with direct exam at day 7	Day 7	Direct exam
Describe ophthalmologic damage to the cornea with direct exam at day 0	Day 0	Direct exam
Describe ophthalmologic damage to the cornea with direct exam at discharge of hospital	Discharge of hospital, up to 3 months	Direct exam
Describe ophthalmologic damage to the cornea with slit lamp exam at day 7	Day 7	Slit lamp exam
Describe ophthalmologic damage to the cornea with slit lamp exam at discharge of hospital	Discharge of hospital, up to 3 months	Slit lamp exam
Describe tear film anomalies at day 7	Day 7	Shirmer test
Describe ophthalmologic damage to the retina at day 0	Day 0	Retinophotography
Describe ophthalmologic damage to the retina at discharge of hospital	Discharge of hospital, up to 3 months	Retinophotography
Describe ophthalmologic damage to the cornea with direct exam at day 14	Day 14	Direct exam
Describe ophthalmologic damage to the cornea with slit lamp exam at day 0	Day 0	Slit lamp exam
Describe ophthalmologic damage to the cornea with slit lamp exam at day 14	Day 14	Slit lamp exam
Describe tear film anomalies at day 14	Day 14	Shirmer test
Describe ophthalmologic damage to the optic nerve at day 7	Day 7	Retinophotography
Describe ophthalmologic damage to the optic nerve at discharge of hospital	Discharge of hospital, up to 3 months	Retinophotography
Describe tear film anomalies at discharge of hospital	Discharge of hospital, up to 3 months	Shirmer test
Describe ophthalmologic damage to the retina at day 7	Day 7	Retinophotography
Describe ophthalmologic damage to the retina at day 14	Day 14	Retinophotography
Describe ophthalmologic damage to the optic nerve at day 0	Day 0	Retinophotography
Describe ophthalmologic damage to the optic nerve at day 14	Day 14	Retinophotography

Trial Locations

Locations (1)

Fondation Adolphe de Rothschild; 🇫🇷 Paris, France