Prevalence of Wound Healing Disturbances in Geriatric Inpatients With Specific Focus on Malnutrition, Other Nutritional Parameters and the Frailty Syndrome (WONDER Study)
试验速览
- 阶段
- 不适用
- 入组人数
- 517
- 试验地点
- 1
- 主要终点
- Prevalence of wound healing disturbances
研究概览
简要总结
In geriatric patients, there is a plethora of nutritional and illness-related parameters, resulting in a complex situation which hampers identification of risk factors.In the planned prospective study, the point and period prevalence of wound healing disorders (WHD) is examined at admission and at discharge in a cohort of 517 male and female geriatric patients. As the investigators are also interested to study the occurrence of WHD in patients with malnutrition (and other geriatric phenomena) compared to the prevalence of WHD in patients with a good nutritional Status.
详细描述
The investigators will determine the prevalence of impaired wound healing upon admission to the hospital as well as the incidence of new wound healing disorders during hospital stay with specific focus on malnutrition and other important nutritional parameters in geriatric patients. Therefore the investigators intend to study consecutively admitted patients both at admission and at discharge and monitor them during hospital stay.
The investigators will investigate the associations between the individual nutritional status and body composition parameters (such as sarcopenia) and WHD in geriatric patients, taking both medical variables and the frailty syndrome into account.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 60 years
- •Informed written consent
- •Normal cognitive status according to Mini-Mental State Examination (MMSE ≥ 24 points)
- •Life expectancy of > 3 months according to treating doctor
- •Proficient in German
排除标准
- •Lack or incapacity of informed consent
- •MMSE < 24
- •Life expectancy < 3 months according to assessment by the attending physician
- •Short term patients (< 3 days of hospital stay)
- •Lack of German language
结局指标
主要结局
Prevalence of wound healing disturbances
时间窗: Baseline
Number of wound healing disturbances upon admission to the hospital in General
次要结局
- Strength Parameter(Baseline and up to 3 weeks)
- Index of quality of life(Baseline and up to 3 weeks, after 3 months and after 6 months)
- Nutritional Parameter(Baseline and up to 3 weeks)
- Frailty(Baseline and up to 3 weeks)
- Functional Parameter(Baseline and up to 3 weeks)
- Body composition(Baseline and up to 3 weeks)
研究者
Kristina Norman
PD Dr. Kristina Norman
Charite University, Berlin, Germany