ISRCTN15320064
Active, not recruiting
Phase 3
Comparing the effectiveness of test and treat approaches with doxycycline or the triple-drug therapy with ivermectin/diethylcarbamazine/albendazole vs ivermectin/albendazole for targeted elimination of lymphatic filariasis in a Phase III clinical trial
Kumasi Centre for Collaborative Research in Tropical Medicine0 sites480 target enrollmentMarch 29, 2022
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Kumasi Centre for Collaborative Research in Tropical Medicine
- Enrollment
- 480
- Status
- Active, not recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age \=5 years
- •2\. LF\-infected person (CFA positive)
- •3\. Able and willing to give informed consent
Exclusion Criteria
- •Specific exclusion criteria for DOX 100 participants:
- •1\. Age \<14 years or \>70 years
- •2\. Body weight \<40 kg
- •3\. Pregnant or breastfeeding women
- •4\. Women of childbearing potential not using an agreed method of contraception (including abstinence; oral contraceptives are not allowed because of interaction with trial drugs)
- •5\. Known hepatic or renal dysfunction or disease of the central nervous system (CNS)
- •6\. History of alcohol or drug abuse
- •7\. History of serious adverse reactions to doxycycline or other tetracyclines
- •8\. History of photosensitivity reactions after taking drugs.
- •9\. Concomitant medication with antacids containing aluminium, magnesium or sucralfate and not able to discontinue
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Not Applicable
Comparison of treatment effectiveness and evaluation of Comparison of treatment effectiveness and evaluation of cost between surgical and non-surgical treatment for gastroesophageal reflux disease (GERD)cost between surgical and non-surgical treatment for gastroesophageal reflux disease (GERD)KCT0003210Korea University Anam Hospital100
Completed
Phase 2
The effect of arthromac plus in the treatment of knee arthritisOsteoarthritis.Osteoarthritis, unspecified siteIRCT20190226042854N1Zanjan University of Medical Sciences54
Not yet recruiting
Phase 1
comparison of two periodontal treatment modality in periodontitisCTRI/2018/11/016391Rajasthan University Of Health Sciences College of Dental Sciences
Not yet recruiting
Not Applicable
Comparison of therapeutic effect and safety of intranasal fluticasone furoate and fluticasone furoate in patients of Chronic Rhinosinusitis: A Randomized, Open Label, Parallel Group StudyHealth Condition 1: J329- Chronic sinusitis, unspecifiedHealth Condition 2: J329- Chronic sinusitis, unspecifiedCTRI/2024/04/064979Govt Doon Medical college
Completed
Not Applicable
Effectiveness and safety of JHG002 for chronic temporomandibular joint dysfunctioDiseases of the digestive systemKCT0004437Jaseng Medical Foundation82