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Clinical Trials/NCT01437462
NCT01437462
Completed
Phase 4

Postoperative Pain After Propofol Sevoflurane Anaesthesia: a Prospective, Randomized, Single-blinded Trial

Tampere University Hospital1 site in 1 country168 target enrollmentOctober 2008
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ConditionsHealthy AdultsGynecological Disease
DrugsSevofluranePropofol

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Healthy Adults
Sponsor
Tampere University Hospital
Enrollment
168
Locations
1
Primary Endpoint
Postoperative consumption of an opioid (oxycodone)
Status
Completed
Last Updated
13 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The impact of anaesthetic method (intravenous vs. inhalational) has been proposed, but not proven in a large-scale study. The researchers aim to provide an investigation that has sufficient power to clarify the potential effect of anaesthetic method on postoperative need of opioids. Sevoflurane and propofol will be compared.

Registry
clinicaltrials.gov
Start Date
October 2008
End Date
March 2013
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Arvi Yli-Hankala

Professor

Tampere University Hospital

Eligibility Criteria

Inclusion Criteria

  • •Age 18-69 years
  • •Gender: female
  • •ASA status 1-3
  • •Laparoscopic hysterectomy

Exclusion Criteria

  • •Body Mass Index over 35
  • •Diabetes mellitus
  • •Liver disease
  • •Allergies to pharmaceuticals used in the Study
  • •Present use of opioids

Outcomes

Primary Outcomes

Postoperative consumption of an opioid (oxycodone)

Time Frame: 20 hours

The consumption of oxycodone will be monitored by recording the amount of the drug received via a commercially available patient controlled analgesia (PCA) pump.

Secondary Outcomes

  • NRS (numeral rating scale) of pain(20 hours)

Study Sites (1)

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