Evaluation of the Clinical Feasibility of Angiographic Flat-detector CT (FDCT) Perfusion Imaging (6sPBV) Technique.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 127
- 试验地点
- 2
- 主要终点
- Performance of flat-detector CT imaging in angiosuite
研究概览
简要总结
The aim of this study is to evaluate the clinical feasibility of the angiographic Flat Detector CT perfusion imaging (6s PBV) technique. The investigators will examine the specific vessel distribution of patients with steno-occlusive disease, treated with a surgical extracranial-intracranial bypass and assess the cerebral perfusion during test occlusion upon a neurovascular treatment and in intracranial tumor patients referred for potential pre-operative embolization.
This study encompasses three scientific objectives:
- What is the selective contribution of an individual bypass artery to the brain perfusion?
- Is a selective intra-arterial angiographic perfusion examination useful in the decision-making of performing pre-operative embolization of intracranial tumors?
- What is the usefulness of performing additive 6s PBV images compared to classical 2D angiography and/or clinical neurological evaluation in case of test occlusion in the evaluation of possible mother vessel occlusion in treatment of complex neurovascular diseases?
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients referred for diagnostics and surgical (extracranial-intracranial bypass) treatment of steno-occlusive neurovascular disorders.
- •Patients referred for hypervascular intracranial tumor resection
- •Patients referred for angiographic test occlusion as part of treatment of complex neurovascular disorders.
排除标准
- •Pregnant women or women trying to get pregnant
- •People younger than 18 years old
- •Patients with thyroid disorders and diabetes, especially those using medication with metformin.
结局指标
主要结局
Performance of flat-detector CT imaging in angiosuite
时间窗: 1 day
The quality of the imaging scans obtained with FDCT will be assessed compared to conventional imaging techniques (CT, angiography and MRI)
次要结局
未报告次要终点
研究者
Thijs van der Zijden
Principal Investigator
University Hospital, Antwerp
