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临床试验/NCT03916133
NCT03916133已完成不适用

Evaluation of the Clinical Feasibility of Angiographic Flat-detector CT (FDCT) Perfusion Imaging (6sPBV) Technique.

University Hospital, Antwerp2 个研究点 分布在 1 个国家目标入组 127 人开始时间: 2018年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
127
试验地点
2
主要终点
Performance of flat-detector CT imaging in angiosuite

研究概览

简要总结

The aim of this study is to evaluate the clinical feasibility of the angiographic Flat Detector CT perfusion imaging (6s PBV) technique. The investigators will examine the specific vessel distribution of patients with steno-occlusive disease, treated with a surgical extracranial-intracranial bypass and assess the cerebral perfusion during test occlusion upon a neurovascular treatment and in intracranial tumor patients referred for potential pre-operative embolization.

This study encompasses three scientific objectives:

  1. What is the selective contribution of an individual bypass artery to the brain perfusion?
  2. Is a selective intra-arterial angiographic perfusion examination useful in the decision-making of performing pre-operative embolization of intracranial tumors?
  3. What is the usefulness of performing additive 6s PBV images compared to classical 2D angiography and/or clinical neurological evaluation in case of test occlusion in the evaluation of possible mother vessel occlusion in treatment of complex neurovascular diseases?

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients referred for diagnostics and surgical (extracranial-intracranial bypass) treatment of steno-occlusive neurovascular disorders.
  • Patients referred for hypervascular intracranial tumor resection
  • Patients referred for angiographic test occlusion as part of treatment of complex neurovascular disorders.

排除标准

  • Pregnant women or women trying to get pregnant
  • People younger than 18 years old
  • Patients with thyroid disorders and diabetes, especially those using medication with metformin.

结局指标

主要结局

Performance of flat-detector CT imaging in angiosuite

时间窗: 1 day

The quality of the imaging scans obtained with FDCT will be assessed compared to conventional imaging techniques (CT, angiography and MRI)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Thijs van der Zijden

Principal Investigator

University Hospital, Antwerp

研究点 (2)

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