The Effect of 5-FU and LMW Heparin on the Rate of Retinal Redetachment After Silicone Oil Removal in Cases of PVR

Phase 3

• Conditions: Proliferative Vitreoretinopathy

• Registration Number: NCT00371020
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

To evaluate the effect of combined 5-FU and low molecular weight heparin in infusion on the rate of retinal redetachment after silicone oil removal in cases of proliferative vitreoretinopathy (PVR).

Detailed Description

Not available

Study Timeline

• Study Start: 2005-02
• Study First Submitted: 2006-08-31
• Study First Submitted QC: 2006-08-31
• Study First Posted: 2006-09-01
• Status Verified: 2007-07
• Study Completion: 2007-07
• Last Update Submitted: 2007-07-11
• Last Update Posted: 2007-07-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Cases with history of vitrectomy and silicone oil injection for management of PVR who undergo silicone oil removal

Exclusion Criteria

• any sign of retinal redetachment before silicone oil removal
• any sign of diabetic retinopathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Retinal redetachment rate

Secondary Outcome Measures

Name	Time	Method
visual acuity
intraocular pressure
reoperation
relative afferent pupillary defect

Trial Locations

Locations (1)

Hamid Ahmadieh, MD; 🇮🇷 Tehran, Iran, Islamic Republic of