Clinical characteristics and natural history of patients with cardiac amyloidosis in King Chulalongkorn Memorial Hospital: a 20-year review

• Conditions: Cardiac amyloidosis in Thailand, focus on clinical manifestation and clinical outcomes.; Cardiac amyloidosis; Transthyretin; ATTR; AL; cardiomyopathy; Natural history; Prognosis

• Registration Number: TCTR20210801002
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-01
• Study Completion: 2022-03-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Adult patients (age >/= 18 yeras)
2. Amyloidosis was diagnosed and followed up in KCMH since 2000
3. At least one of following investigations suspected amyloidosis
(1) ECG, (2) Echocardiography, (3) Cardiac MRI
4. At least one of following investigations compatible with amyloidosis
(1) Pathological finding demonstrate amyloid fibrils, (2) 99mTc-PYP uptake compatible with cardiac amyloidosis

Exclusion Criteria

None of investigation (ECG, Echocardiography, cardiac MRI) demonstrate the suspected cardiac amyloidosis

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Death time since diagnosis death rate

Secondary Outcome Measures

Name	Time	Method
Cardiac arrhythmia time after diagnosis event rate,Coronary artery disease time after diagnosis Event rate,Heart failure hospitalization time after diagnosis event rate,Medication time after diagnosis dosage