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Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age: RhinoPOC RCT

Phase 1
Recruiting
Conditions
Rhinovirus-induced Wheezing
Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]
Registration Number
CTIS2024-512561-13-00
Lead Sponsor
niversity Of Oulu
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
210
Inclusion Criteria

Age 6 months to 2 years, Acute wheezing diagnosed by an emergency department physician, Positive rhinovirus- or other picornavirus in nasal swap, Arrival at the hospital within the past 6 hours, Salbutamol treatment at the emergency department

Exclusion Criteria

Need for immediate resuscitation, Active chickenpox infection, Suspected foreign body in respiratory tract, Immunosuppressive treatment, Systemic glucocorticoid treatment within the previous 14 days, Allergy to glucocorticoids, Need for immediate transfer to an intensive care unit, Suspected pneumonia in auscultation, Suspected serious bacterial infection, Positive RS-virus in nasal swab, Positive SARS-CoV-2 in nasal swab, Positive Mycoplasma pneumoniae in nasal swab, Positive Bordetella pertussis in nasal swab, Chickenpox exposure within the previous 14 days

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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