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临床试验/NCT07564011
NCT07564011尚未招募不适用

Comparison Between Medial Patellofemoral Ligament Reconstruction Alone Versus Combined MPFL & Medial Patellotibial Ligament Reconstruction in the Management of Recurrent Lateral Patellar Dislocation in Children

Assiut University0 个研究点目标入组 22 人开始时间: 2026年6月17日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
22
主要终点
Kujala Score for knee function

研究概览

简要总结

Patellofemoral instability (PFI) is a common condition that may result from numerous underlying soft tissue and bony abnormalities, and can significantly impact the patients' quality of life and function. It is estimated that PFI affects between 5.8 and 29 out of every 100,000 children aged 10 to 17 years [1].

Patellar instability is defined as a symptomatic deficiency of the passive constraint such that the patella may escape partially or completely from its anatomic position with respect to the femoral trochlea under the influence of a displacing force. Such a displacing force could be generated by muscle tension, movement, and/or externally applied forces [2].

The etiology of RPD is multifactorial, including medial patellofemoral ligament (MPFL) injuries, abnormally lateralized tibial tubercle (TT), femoral trochlear dysplasia, patella alta, increased femoral anteversion and genu valgum [3,5].

The MPFL is the primary static soft tissue restraint which restrains against lateral subluxation and dislocation of the patella, especially between 0° and 30° of knee flexion [3]. And the MPTL act as secondary restraint[4.]

Therefore, injury or deficiency of MPFL is one of the predisposing factors for RPD.Therefore, an anatomical repair MPFL is necessary to prevent redislocation of patella [6].

MPFL reconstruction is widely recognized as an important component of the current treatment for recurrent patellar instability, MPTL reconstruction improve medial patellar stabilization, patellar tilt, patellar rotation as well as decreases stress on MPFL.A large number of surgical methods for treating patellofemoral instability have been described in various studies, but the best method is still controversial[7].

This study is prepared to compare the results of MPFL reconstruction versus combined MPFL and MPTL reconstruction in management of recurrent lateral patellar dislocation in children .

详细描述

Patellofemoral instability (PFI) is a common condition that may result from numerous underlying soft tissue and bony abnormalities, and can significantly impact the patients' quality of life and function. It is estimated that PFI affects between 5.8 and 29 out of every 100,000 children aged 10 to 17 years [1].

Patellar instability is defined as a symptomatic deficiency of the passive constraint such that the patella may escape partially or completely from its anatomic position with respect to the femoral trochlea under the influence of a displacing force. Such a displacing force could be generated by muscle tension, movement, and/or externally applied forces [2].

The etiology of RPD is multifactorial, including medial patellofemoral ligament (MPFL) injuries, abnormally lateralized tibial tubercle (TT), femoral trochlear dysplasia, patella alta, increased femoral anteversion and genu valgum [3,5].

The MPFL is the primary static soft tissue restraint which restrains against lateral subluxation and dislocation of the patella, especially between 0° and 30° of knee flexion [3]. And the MPTL act as secondary restraint[4.]

Therefore, injury or deficiency of MPFL is one of the predisposing factors for RPD.Therefore, an anatomical repair MPFL is necessary to prevent redislocation of patella [6].

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
— 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • a. Inclusion criteria:
  • Age : <18years old.
  • History of recurrent lateral patellar dislocation (>2 episodes).
  • Failure of conservative treatment. -

排除标准

  • b. Exclusion criteria:
  • Active infection.
  • inflammatory joint disorders.
  • trochlear dysplasia
  • previous surgeries related to patella dislocation -

研究组 & 干预措施

Combined MPFL and MPTL for Recurrent patellar displacement in children

Experimental

MPFL +MPTL Reconstruction

干预措施: MPFL + MPTL Reconstruction (Procedure)

MPFL Reconstruction For Recurrent patellar displacement in children

Experimental

MPFL reconstruction

干预措施: MPFL Reconstruction (Procedure)

结局指标

主要结局

Kujala Score for knee function

时间窗: 12 months post operative

Lysholm score for knee function

时间窗: 12 month

Redislocation rate

时间窗: 12 months

次要结局

  • Range of motion(12 month)
  • Complications(12months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Kerolus Waheed Fuad Bakhit

Principal investigator

Assiut University

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