To measure biological markers in blood and urine sample of preterm babies
Not Applicable
Completed
- Conditions
- Health Condition 1: H351- Retinopathy of prematurity
- Registration Number
- CTRI/2019/10/021769
- Lead Sponsor
- Government medical college and hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 71
Inclusion Criteria
Group A include Neonates with Type 1 ROP
Group B include Neonates without any ROP matched by gestation within 1 week for neonates enrolled in group A
Exclusion Criteria
Infants with Congenital abnormalities
Infants born to mother with gestational metabolic diseases
TORCH infections suspicion on eye examination
Hydrocephalus
Necrotising enterocolitis
Periventricular leukomalacia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare inflammatory (Interleukin-6 and Interleukin-8) and angiogenic (Vascular endothelial growth factor) biomarkers in preterm babies with or without Type 1 Retinopathy of prematurity <br/ ><br>To study the association of systemic biomarkers with the stage and zone of Retinopathy <br/ ><br>of prematurity <br/ ><br> <br/ ><br>Timepoint: AT 18 months
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI