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The efficacy and safety in canaglifrozin therapy for diabetes complicated by non-alcoholic fatty liver disease.

Not Applicable
Conditions
onalcoholic fatty liver disease type 2 diabetes mellitus
Registration Number
JPRN-UMIN000023044
Lead Sponsor
Kyoto prefetural University of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
20
Inclusion Criteria

Not provided

Exclusion Criteria

administration of SGLT2 inhibitors type 1 diabetes platelet count<100000/microL eGFR<45m/min/1.73m2 diagnosed heart failure or malignancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
serum level of ALT at baseline and end of 12 weeks. The change of ALT between baseline and end of 12 weeks administration.
Secondary Outcome Measures
NameTimeMethod
serum level of AST, GGT, ALP, HbA1c, fasting glucose, fasting insulin, c peptide, platelet count, uric acid, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, hyaluronic acid, type 4 collagen 7s. waist circumference, NAFIC score, FIB-4 index, FM-fibro index, body composition, LSM, CAP, DEBQ, SF-8TM
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