Effectiveness of Permethrin Impregnated Underwear in Preventing Louse Proliferation in Infected Homeless
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 125
- 试验地点
- 1
- 主要终点
- Show that underwear soaked with permethrine in 8 % allow to reduce in a long-lasting way (J90 and J365) of 50 % the index of infestation and prevalency of the louses in the group treated with regard to the group placebo.
研究概览
简要总结
Homelessness, also name the fourth world, is a growing public health problem worldwide. Previous studies showed that up to 30% of the homeless people reported pruritus that often results in itchy lesions, which expose them to bacterial skin infections.
The investigators therefore conducted a randomized, double-blind, placebo-controlled trial to test the hypothesis that a single oral dose of ivermectin was effective in significantly reducing the prevalence of pruritus in a sheltered homeless population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient HOMELESS PERSON " individual who has no regular access to a conventional residence ", appearing during the period of study at reception centers (Forbin or Madrague Ville) and being in the habit of wearing there (at least 4 times a week),
- •Male genital organ and feminine,
- •Of more than 18 years old,
- •Presenting of the prurit, hurts of scratching or the louses
- •Wishing to change his underwear,
- •Having given his lit(enlightened) consent
排除标准
- •Woman presenting a sexually transmitted infection (infection with gonococcus, with Chlamydia trachomatis, with Trichomonas vaginalis) revealing on the takings realized during the consultation of inclusion but the bacteriological results of which will be known only secondarily.
- •Pregnant Woman presenting to the consultation of inclusion of métrorragies either a break of the pocket of waters or an infectious complication of the pregnancy.
- •Woman removing her consent during the study.
- •Lost sight Woman.
- •Woman deprived of freedom, judicial or administrative;
- •Woman hospitalized for quite other reason that looks for her(it);
- •Woman hospitalized in a sanitary establishment or social in the other purposes that the research;
- •Major Woman except state to express its consent
研究组 & 干预措施
no permethrin
干预措施: no Permethrin impregnated (Drug)
permethrin
干预措施: Permethrin impregnated (Drug)
结局指标
主要结局
Show that underwear soaked with permethrine in 8 % allow to reduce in a long-lasting way (J90 and J365) of 50 % the index of infestation and prevalency of the louses in the group treated with regard to the group placebo.
时间窗: 2 YEARS
次要结局
- Show that underwear soaked with permethrine in 8 % allow to reduce in a long-lasting way (J90 and J365) of 50 % the index of infestation and prevalency of the louses in the group treated with regard to the group placebo.(2 years)