The effects of doxycycline treatment on inflammation and endothelial function in advanced atherosclerosis
Completed
- Conditions
- atherosclerosis, peripheral arterial disease, inflammation, Doxycycline
- Registration Number
- NL-OMON23404
- Lead Sponsor
- none
- Brief Summary
In progress
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
1. Patients suffering from mild to moderate stable peripheral arterial disease who do not require carotis or femoral endarteriectomy (Fontaine IIa)
Exclusion Criteria
1. Known hypersensitivity for tetracycline derivates
2. Patients treated with antibiotics in last 3 months for other diseases then lower urinary tract infections
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endothelial function
- Secondary Outcome Measures
Name Time Method Plasma markers