Modeling Clinical Outcomes in Gambling Addiction

Not yet recruiting

• Conditions: Gambling Disorder

• Registration Number: NCT06981546
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Gambling disorder (GD) is recognized as an addictive disorder. Financial consequences of GD are often dramatic, inducing professional, familial, legal and medical repercussions and particularly mental health consequences.

MOGADOR is a longitudinal, multicentric, prospective, prognostic study, which aims to identify factors predicting the evolution of french patients with GD in care centers particularly involved in the management of GD. The main goal will focus on evolution of DSM-5 (Diagnostic and Statistical Manual of Mental Disorder 5th edition) GD criteria during the first year of follow-up. The prognostic factors will be collected at base-line and they will be considered to influence the long-term prognosis of patients.

For patients suffering of GD, our main hypothesis is that initial factors like individual socio-demographic characteristics, clinical psychiatric profiles, addiction comorbidities, and behaviour are associated with the clinical prognosis (total remission of DSM-5 criteria of GD at 12 months).

MOGADOR will be the first study, aiming to model prognostic aspects of GB in populations specially monitored for this disorder.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-05
• Study First Submitted: 2025-05-05
• Study First Submitted QC: 2025-05-13
• Last Update Submitted: 2025-05-13
• Study First Posted: 2025-05-20
• Last Update Posted: 2025-05-20
• Study Start: 2025-09-01
• Primary Completion: 2029-09-01
• Study Completion: 2030-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 268

Inclusion Criteria

• Patient, male or female, over 18 years old, consulting in one of the participating centers.
• DSM-5 criteria for gambling disorder at inclusion: at least 4 criteria present in the 12 months preceding the study.
• First treatment for gambling disorder or no treatment in the last 6 months (initiation or re-initiation of care).

Exclusion Criteria

• Unable to be reached by phone.
• Unable to use the internet.
• Patient under antiparkinsonian treatment of the dopaminergic family.
• Being treated with a drug that may trigger/increase symptoms of gambling disorder (e.g. dopamine agonist).
• Subject under guardianship.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Partial remission of gambling disorder at 12 months (strictly less than 4 DSM-5 criteria)	DSM-5 criteria assessment will be conducted at 9 and 12 months after inclusion.	Assessment of DSM-5 criteria will be performed by the clinician, and by a previously trained CRA if clinical follow-up is discontinued.
modeling prognostic factors	at inclusion visit.	The prognostic factors, studied will be: number of initial DSM-5 criteria, gender, age, marital status, housing, employment status, socioeconomic level, time spent gambling, impulsivity, type of gambling, location of gambling, and also the factor with the strongest association in univariate analysis among the following factors: * Depression (PHQ scale),; * Anxiety (GAD scale),; * Quality of life (SF-36 scale).

Trial Locations

Locations (9)

Hôpital Jen Minjoz, CHU de Besançon; 🇫🇷 Besancon, France

Service Universitaire d'Addictologie de Lyon (SUAL), CH Le Vinatier; 🇫🇷 Bron, France

Service Universitaire d'Addictologie de Lyon (SUAL), Groupement Hospitalier Est; 🇫🇷 Bron, France

Service Universitaire d'Addictologie, CHU de Clermont-Ferrand; 🇫🇷 Clermont-ferrand, France

Name of location * Service d'Addictologie, Groupe Hospitalier Seclin Carvin; 🇫🇷 Lille, France

Centre Expert Régional du Jeu Pathologique (CERJeP Limousin); 🇫🇷 Limoges, France

Service Universitaire d'Addictologie, CHU de Nîmes; 🇫🇷 Nimes, France

Assistance Publique des Hôpitaux de Paris, Hôpital Marmottan; 🇫🇷 Paris, France

Hôpital de Bellevue, CHU de St-Etienne; 🇫🇷 St-etienne, France