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Efficacy and safety of mild moxibustion in the treatment of diarrhea-predominant irritable bowel syndrome (spleen deficiency and dampness excess syndrome): A study protocol for a randomized controlled trial

Phase 1
Registration Number
TCTR20230523002
Lead Sponsor
ijiang Ji
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
92
Inclusion Criteria

1.Patients should meet both TCM and Western diagnostic criteria of IBS-D;
2.Patients at age of 18 to 65 years old;
3.No history of relevant treatment before enrollment or with discontinuation of treatment with Chinese medicine, antidiarrheal drugs and antispasmodics for more than 1 month;
4.The total score of the IBS Severity Scoring System score(IBS-SSS) is more than 75;
5.Voluntary participation in this study and signing of the informed consent form.

Exclusion Criteria

1.Patients with IBS-C, IBS-M, and IBS-U;
2.Patients with inflammatory bowel disease, organic intestinal lesions, peptic ulcer, infectious diarrhea;
3.Patients combined with severe cardiovascular, hepatic, renal, endocrine and hematopoietic system diseases; patients with other diseases other than diarrhea that may affect the test results that cannot be discontinued; patients with mental illness;
4.Patients who are pregnant or lactating, and those who have a birth plan from their enrollment to 1 month after the end of the trial;
5.Those who have participated in other clinical trials within 1 month.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
IBS-SSS 8 weeks includes five aspects with a score range of 0 to 100 out of 500 for each indicator
Secondary Outcome Measures
NameTimeMethod
Irritable Bowel Syndrome-Quality of Life(IBS-QOL)score 8 weeks The score of Irritable Bowel Syndrome-Quality of Life
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