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临床试验/JPRN-jRCTs041200061
JPRN-jRCTs041200061已完成1 期

Development of Antibacterial Photodynamic Periodontal Therapy for Lasers using Biological Window of Optical Properties

Fukuda Mitsuo0 个研究点目标入组 40 人开始时间: 2020年11月10日最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
40

研究概览

简要总结

In the new a- PDT (antibacterial photodynamic therapy by irradiation from outside the periodontal pocket), a decrease in the viable CFU count immediately after treatment was observed under the conditions obtained in the basic study, However, the effect was not recognized but one week later. It is necessary to revise the irradiation conditions. However, the ratio of Gram(-) bacteria was significantly reduced in the experimental group, indicating that the bacterial flor

研究设计

研究类型
Interventional

入排标准

年龄范围
>= 20age old 至 <= 85age old(—)
性别
All

入选标准

  • (1) Healthy adults with periodontal disease as follows,
  • 1) who have single-root teeth with over 5mm residual pockets depth.
  • 2) who have stable occulusion.
  • (2) Patients aged from 20 to 85 years old at registration.
  • (3) Patients who have written informed content to participate in this study for 2 consecutive weeks.

排除标准

  • (1) Patients who have taken antibiotics within the last 3 months.
  • (2) Patients with diabetes.
  • (3) Patients who have taken or taking anticancer drugs within 6 months.
  • (4) Patients with a history of allergy to indocyanine green.
  • (5) Patients with a history of allergy to crustaceans.
  • (6) Women who are pregnant, breastfeeding or may or may be pregnant.

研究者

发起方
Fukuda Mitsuo

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