Benefits of using two different local anaesthetics, bupivacaine and ropivacaine with fentanyl for pain relief in labouring parturients

Not yet recruiting

• Conditions: Encounter for full-term uncomplicated delivery,

• Registration Number: CTRI/2019/06/019917
• Lead Sponsor: Dr Sofiya Memon

Brief Summary

Labour analgesia with use of epidural local anaesthetics and opioids is routinely used technique for pain relief in labour. My study compares the effect of two different local anaesthetics Bupivacaine and Ropivacaine  when used with same amount of low dose opioid fentanyl. Such study camparing effects of same concentration [0.125%] of  two different local anaesthetics have not been done previously in our institute and will help in determining the benefits if any of one local anaesthetic over another.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-07
• Last Update Posted: 2019-06-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 44

Inclusion Criteria

• ASA Physical status II 2.
• Singleton Pregnancy 3.
• Term Pregnancy 4.
• Vertex presentation 5.
• Request for Neuraxial Analgesia.

Exclusion Criteria

• Parturients who had cervical dilatation >5 cm 2.
• Patients who had received Parentral opioids <2 hour earlier 3.
• Parturients with Obstetric complication such as Pre eclampsia, Eclampsia, multiple pregnancies, macrosomia, diabetes, heart disease, cephalopelvic disproportion, Malpresentation 3.
• Coagulation defect 4.
• Vertebral anomaly 5.
• Local sepsis 6.
• Sensitivity to drug- Bupivacaine and Ropivacaine.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of Analgesia	from Onset of analgesia which is Vas less than 3 to request for additional Analgesia considered when patient feels contraction is uncomfortable. VAS is accessed every 5 minutes untill VAS is less than 3. than every 15 minutes

Secondary Outcome Measures

Name	Time	Method
Highest level of sensory block, Side effects, Mode of Delivery, Maximum Motor Block, Haemodynamic Changes i.e., Heart rate, Mean blood pressure, sPO2.	at 5, 10, 15, 30, 60 min then every 60 min

Trial Locations

Locations (1)

Dr Bhimrao Ambedkar Memorial Hospital & Pt J N M Medical College, Raipur; 🇮🇳 Raipur, CHHATTISGARH, India

Dr Bhimrao Ambedkar Memorial Hospital & Pt J N M Medical College, Raipur

🇮🇳Raipur, CHHATTISGARH, India

Dr Sofiya Memon

Principal investigator

8109299668

sofiyamemon786@gmail.com