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The effect of flavonoids and vitamin C on periodontitis

Conditions
Periodontitis - ParodontitisVitamin C - Vitamine CFlavanoids - FlavonoidenQuercetin - Quercetine
Registration Number
NL-OMON22290
Lead Sponsor
Academic Centre for Dentistry Amsterdam (ACTA)University of Amsterdam (UVA) and Vrije Universiteit (VU) AmsterdamGustav Mahlerlaan 3004, 1081 LA AmsterdamThe Netherlands
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
81
Inclusion Criteria

age: ≥18 years;

- proximal bone loss of ≥ 3mm in 2 non-adjacent teeth;

Exclusion Criteria

- diagnosis of any acute periodontal problem which requires immediate treatment;

- use of antibiotics within the previous 6 months;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary response variable of the present study with respect to the clinical measurements is bleeding on pocket probing (bop).
Secondary Outcome Measures
NameTimeMethod
With regard to the systemic inflammatory biomarkers HbA1C, hs-CRP, and vitamin C (from venous blood).
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