Oxygen Level and Safe Emergence From Anesthesia

Not Applicable

Completed

• Conditions: Focus of Study is Postoperative Pulmonary Atelectacis
• Interventions: Procedure: 100% oxygen; Procedure: 30% oxygen

• Registration Number: NCT01779076
• Lead Sponsor: Region Västmanland

Brief Summary

Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-01-28
• Study First Submitted QC: 2013-01-28
• Study First Posted: 2013-01-30
• Study Start: 2013-02
• Primary Completion: 2013-06
• Study Completion: 2013-06-11
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-14
• Last Update Posted: 2018-01-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

• No sign of difficult airway or intubation
• Day case surgery in total intravenous anesthesia with laryngeal mask airway without adding regional anesthesia of plexus brachialis or muscle relaxant.
• Body mass index less than 35.
• American Society of Anesthesiologists physical status (ASA) class I-III

Exclusion Criteria

• Body mass index 35 or higher
• Increased risk of aspiration
• Obstructive sleep apnea syndrome
• Procedures during surgery making a former easy airway a difficult airway
• Need for opioids after extubation
• Hypothermia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
100% oxygen during extubation	100% oxygen	In this arm the intervention will consist of 100 % oxygen.
30% oxygen during extubation	30% oxygen	In this arm the intervention will consist of 30 % oxygen.

Primary Outcome Measures

Name	Time	Method
Area of atelectasis	30 minutes	The area of atelectasis is investigated by computed tomography of the lungs postoperatively

Secondary Outcome Measures

Name	Time	Method
Peripheral oxygen saturation (SpO2)	3 hours	SpO2 is continuously assessed postoperatively.

Trial Locations

Locations (1)

Västmanlands sjukhus Köping; 🇸🇪 Köping, Västmanland, Sweden