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临床试验/NCT01750047
NCT01750047已完成不适用

A Epidemiological Survey of Preoperative Pain Perception and Postoperative Pain in Chinese Population

Xianwei Zhang1 个研究点 分布在 1 个国家目标入组 1,327 人开始时间: 2012年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
1,327
试验地点
1
主要终点
Pressure pain tolerance

研究概览

简要总结

Object: Every person's pain perception and possible postoperative pain is different. As the investigators know, they are affected by many factors. However, the investigators don't know whether the smoking factors, alcohol factors, surgery type, education background, etc. will affect individual pain perception and possible postoperative pain in Chinese population. This study was conducted to investigate the power of these possible affect factors. Method: Patients receiving elective surgery under general anesthesia were recruited into this study. The investigators measured their preoperative pressure pain threshold (PPT) and pressure pain tolerance (PTO)and also investigated the patient's personal information of smoking factors, alcohol factors, surgery type, education background, etc. In addition, we retrospectively investigated the visual analog scale (VAS) during patient-controlled analgesia (PCA) treatment 0 to 48 h after operation as well as the PCA press frequency and drug consumption of those patients who received PCA administration.

详细描述

Patients with the following diseases were excluded: known history of chronic pain, psychiatric diseases or communication disorders, diabetes mellitus, severe cardiovascular diseases, kidney or liver diseases with poor hepatic function, alcohol or pregnancy or at the lactation period.

研究设计

研究类型
Observational
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18 to 70
  • The right hand is handedness
  • Agreed to participate the research
  • Not with known chronic disease
  • Not taking analgesics within 3 months

排除标准

  • History of chronic pain diseases
  • Diabetes mellitus
  • Severe cardiovascular diseases
  • Kidney or liver diseases
  • Alcohol or drug abuse
  • Pregnancy or at lactation period
  • Disagree to participate to the research

结局指标

主要结局

Pressure pain tolerance

时间窗: 1 year

Pressure pain threshold

时间窗: 1 year

次要结局

  • Pain scores on visual analog scale after operation(1 year)
  • Opioid consumption dose after operation(1 year)

研究者

发起方
Xianwei Zhang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Xianwei Zhang

Clinical Professor

Huazhong University of Science and Technology

研究点 (1)

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