Effect of topical aqueous extract of pistachio (Pistacia Vera L.) pericarp on knee osteoarthritis: A randomized double-blind controlled clinical trial

Rafsanjan University of Medical Sciences0 个研究点目标入组 75 人开始时间: 待定最近更新: 2021年11月29日

适应症

试验速览

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•age 45-70 years old
•diagnosis of knee osteoarthritis will be based on American College of Rheumatology (ACR) criteria, which will be approved by a specialist in rheumatology
•the presence of moderate knee pain within 24 hours will be based on Visual Pain Scale (VAS) to 4–7 cm

•Patients with inflammatory diseases (such as lupus, rheumatoid arthritis, a history of brucellosis, etc.)
•cancer or other serious diseases
•symptoms or history of liver or kidney failure
•Taking oral corticosteroids in the past 4 weeks
•corticosteroid injection during the last 6 months
•continuous use of herbs
•smoking and drugs
•allergy to pistachios
•consuming of dietary and medicinal supplements
•consumption of pistachios during the two weeks before the start of the test
•Regular daily use of painkillers and very advanced disease
•use of other topical drugs at the site of drug use
•oral use of other analgesics and other effective compounds in the treatment of osteoarthritis up to 10 days before the study
•skin or infectious disease or wound at the site of drug use

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