Closing the Gap: Early Intervention for Cognitive Disability After Stroke
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Strategy Training
- Sponsor
- University of Pittsburgh
- Enrollment
- 128
- Locations
- 1
- Primary Endpoint
- Change in Independence with Daily Activities
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Individuals with cognitive impairments after stroke sustain significant disability in their daily tasks, and account for a significant proportion of stroke-related healthcare costs. The proposed study examines a novel intervention, strategy training, that shows promise for helping individuals with stroke-related cognitive impairments reduce disability in daily tasks, which may lead to reductions in healthcare costs. We predict that strategy training will result in significantly greater independence 6 months after stroke compared to an attention control intervention, and that strategy training may reduce cognitive impairments.
Investigators
Elizabeth R. Skidmore, PhD, OTR/L
Assistant Professor
University of Pittsburgh
Eligibility Criteria
Inclusion Criteria
- •primary diagnosis of acute stroke
- •admission to acute inpatient rehabilitation
- •impairment in higher order cognitive functions (EXIT-14 ≥ 3)
Exclusion Criteria
- •pre-stroke diagnosis of dementia in the medical record
- •inability to follow two- step commands 80% of the time
- •severe aphasia (BDAE ≤ 1)
- •current major depressive, bipolar, or psychotic disorder
- •drug or alcohol abuse within 3 months
Outcomes
Primary Outcomes
Change in Independence with Daily Activities
Time Frame: Baseline to Month 6
Moderate effect size of difference between groups in independence (measured with the Functional Independence Measure)
Secondary Outcomes
- Change in Executive Functions(Baseline to Month 6)