CTRI/2022/06/043333尚未招募不适用
Comparative evaluation of topical calcipotriol plus Narrow Band ultraviolet B phototherapy versus topical calcitriol plus Narrow Band ultraviolet B phototherapy in treatment of psoriasis
Kamal Aggarwal1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2022年6月25日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To compare efficacy between topical calcipotriol and topical calcitriol
研究概览
简要总结
To compare the clinical efficacy and safety of topical calcipotriol ointment with narrow band ultraviolet-B phototherapy versus topical calcitriol ointment and narrow band Ultraviolet-B phototherapy in the treatment of psoriasis.
To compare the safety of the two combinations by assessing the adverse effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 19.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with stable plaque psoriasis not exceeding 50% of body surface area involvement of age more than 18 years, according to the rule of nine, was included in this study.
排除标准
- •â€¢Patients of age 18 years and below.
- •â€¢Patients who have used systemic antipsoriatic treatment or phototherapy within 2 months prior to the study.
- •â€¢Patients having intolerance or previous failure to phototherapy.
- •â€¢Patients using phototoxic drugs or drugs influencing psoriasis (lithium, beta blockers etc).
- •â€¢Patients with hypersensitivity to calcipotriol or calcitriol.
- •â€¢Patients with known hypercalcemia or hypersensitivity to calcipotriol.
- •â€¢Patients with a history suggestive of photosensitivity or polymorphic light eruptions.
- •â€¢Patients with previous or current carcinoma of the skin or actinic keratosis.
- •â€¢Pregnant patients or lactating mothers.
结局指标
主要结局
To compare efficacy between topical calcipotriol and topical calcitriol
时间窗: to compare the difference of calcipotriol and calcitriol over 12 week period
次要结局
- To compare the safety of the two combinations by assessing the adverse effects.(1 year)
研究者
研究点 (1)
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