The effect of synbiotic supplementation on anthropometric indices, Inflammatory and hormone profiles in patients with hypothyroidism

Esfahan University of Medical Sciences0 个研究点目标入组 56 人开始时间: 待定最近更新: 2019年1月14日

适应症

试验速览

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•Age of 18 to 65 years
•Hypothyroid patients with a history of treatment for more than one year using levothyroxine (sodium)
•TSH is at least one year with a constant dose of levothyroxine in the normal range
•No smoking and alcohol
•Non pregnant, non-lactating
•Non-use of drugs that affect metabolism and absorption of levothyroxine include: iron sulfate, magnesium sulfate, warfarin, luvastatin, amiodarone, sumatropin, calcium carbonate, orlistat, multivitamin and minerals, theophylline, ritunavir, rifampin, phenytoin, karmazapine, Phenobarbital, Sucralfate, Aluminum hydroxide, Sertraline, Bile doses, Estrogens and other estrogen modifying drugs, Proton pump suppressants, Phosphate binders
•People who, after explaining the work, were willing to cooperate and answer questions and conduct experiments

•Thyroid cancer
•Intestinal malabsorption (history of obstructive surgery, inflammatory bowel disease, celiac disease)
•Antibiotic use
•Acute and chronic infectious diseases
•Use of drugs that affect the absorption and metabolism of levothyroxine, including (iron sulfate, magnesium sulfate, warfarin, luvastatin, amiodarone, sumatropin, calcium carbonate, orlistat, multivitaminomineral, theophylline, ritunavir, rifampin, Tween, Karmazpine, Phenobarbital, Sucralfate, Aluminum Hydroxide, Sertraline, Bile Drug, Estrogen and other estrogen modifying drugs, proton pump inhibitor drugs, phosphate binders)

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